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Stem Cell Therapy in a Caprine Model of Osteoarthritis

J. Mary Murphy, David J. Fink, Ernst B. Hunziker, and Frank P. Barry

Mesenchymal stem cells (MSCs) have the capacity to differentiate into a variety of connective tissue cells (1–4) including …

State of the Art and Future Perspectives of Articular Cartilage Regeneration: a focus on Adipose-Derived Stem Cells and Platelet-Derived Products

F. Hildner, C. Albrecht C. Gabrie, H. Redl, and M. van Griensven

1. The difficulty of treating articular cartilage lesions Trauma, erroneous biomechanically defective positioning and age-related degeneration often result …

Mesenchymal Stem Cells for the Treatment of Cartilage Lesions: from Preclinical Findings to Clinical Application in Orthopaedics

Giuseppe Filardo, Henning Madry, Mislav Jelic, Alice Roffi, Magali Cucchiarini, Elizaveta Kon

Introduction Articular cartilage lesions are a debilitating disease resulting in fibrillation and subsequent degradation which can also involve …

Mesenchymal Stem Cells for Cartilage Repair in Osteoarthritis

Pawan K Gupta, Anjan K Das, Anoop Chullikana, and Anish S Majumdar

Introduction The knee joint is a marvel of engineering that acts as a conduit for transferring the weight …

Mesenchymal Stem Cell Sheet Encapsulated Cartilage Debris Provides Great Potential for Cartilage Defects Repair in Osteoarthritis

Yiying Qi, Weiqi Yan

Osteoarthritis (OA) is a degenerative disease of the articular cartilage. Drug interventions for OA primarily aim to alleviate …

Marrow Stimulating Technique to Augment Meniscus Repair

Kevin B. Freedman, M.D., M.S.C.E., Shane J. Nho, B.A., and Brian J. Cole, M.D., M.B.A.

The rate of healing after meniscus repair varies in the literature from 63% to 91%. The rate of healing …